Questions as to variations of skin color, stature; deformation of the head, rickets and deformity; speckled Indians; length of nursing; child-rearing; fertility; life-span; old age; insanity; suicide; plucking of hair; diseases. He seeks vocabularies of the Seneca, Tuscarora, Wyandot, and Cochnawaga.
Numbered responses to Barton's inquiries concerning Algonquian and "Iroquois Indians" [Haudenosaunee], similar in content to Zeisberger-Senseman answers, though more general.
A form letter, describing enclosures (missing): a standard vocabulary, including words of Catherine the Great; a list of verb forms and sentences; and a list of tribes and languages arranged by Albert Gallatin. Recommends use of Pickering orthography.
Note: 'papers which were lost in the trunk no. 28 found on the S. side of the river 3 or 4 miles above Manchester and returned to me by Mr. Jefferson July 2, 1809.'